1cP-MiPLA

1cP-MiPLA: Lysergamide Research Chemical Overview and Scientific Use

1cP-MiPLA (1-cyclopropionyl-N-methyl-N-isopropyl lysergamide) is a semi-synthetic lysergamide derivative structurally related to LSD. It is of growing interest in research settings for its potential as a serotonin receptor agonist, particularly within the 5-HT2A receptor pathway—a key area of study in modern psychedelic science.

Like other lysergamides such as 1P-LSD and 1V-LSD, 1cP-MiPLA may act as a prodrug, meaning it is believed to convert into an active compound in vivo, potentially MiPLA or LSD. However, this hypothesis is still under investigation and lacks formal peer-reviewed validation.

Chemical Profile and Classification

  • Full Name: 1-cyclopropionyl-N-methyl-N-isopropyl lysergamide

  • Molecular Formula: C23H29N3O2

  • Class: Lysergamide / Ergoline derivative

  • Common Form: Blotters or microgram-dosed powder for lab analysis

  • Applications:

    • Receptor binding assays

    • Structure-activity relationship (SAR) studies

    • Comparative metabolism research

    • Psychedelic pharmacology modeling

1cP-MiPLA’s structural substitutions—notably the cyclopropionyl group—make it chemically distinct from LSD while still retaining key features that allow it to interact with serotonin receptors, making it an important molecule in psychedelic neuroscience research.

Scientific Relevance

Although no formal toxicological or clinical studies have been published, 1cP-MiPLA is considered a research candidate for understanding lysergamide activity at various neurotransmitter systems. Unverified lab reports and limited anecdotal discussions suggest:

  • A slightly altered onset and duration compared to LSD analogs

  • Lower potency relative to 1P-LSD or 1V-LSD

  • A subtle, qualitative difference in receptor binding affinity

  • Similar safety profile in controlled research settings (with caution)

These findings remain speculative and are not suitable for human testing or consumption.

Lab Handling and Storage

1cP-MiPLA is a high-potency research chemical. Proper handling and secure lab protocols are required for all analytical work.

Safety procedures include:

  • Handling in a fume hood or ventilated space

  • Use of gloves, goggles, and protective clothing

  • Storage in airtight containers, away from heat and light

  • Documentation of batch numbers and research purposes

  • Use of microgram-scale measurement tools

Legal Status of 1cP-MiPLA

As a relatively new compound, 1cP-MiPLA is not explicitly scheduled in many jurisdictions. However, due to its structural similarity to LSD, it may be regulated under analogue laws or broad-spectrum psychoactive substance legislation.

  • United States: Likely considered an LSD analog under the Federal Analog Act

  • UK: May fall under the Psychoactive Substances Act (PSA)

  • Germany: Covered under the NpSG as a non-approved psychoactive substance

  • EU: Regulatory status varies by country

  • Canada/Australia: Subject to analogue and customs restrictions

Always verify legal status in your country before acquiring or working with 1cP-MiPLA.

For Research Use Only

1cP-MiPLA is not for human consumption or clinical use. This compound is supplied strictly for analytical, forensic, and scientific purposes in qualified laboratory environments.

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