3-CL-PCP

3-CL-PCP: Research Chemical Profile, Structure, and Legal Status

3-CL-PCP (3-Chlorophencyclidine) is a dissociative research chemical from the arylcyclohexylamine class, structurally related to PCP (phencyclidine) and 3-MeO-PCP. It has gained attention in forensic and academic research settings due to its potential NMDA receptor antagonism and structural properties.

Although it shares some chemical similarities with controlled dissociatives, 3-CL-PCP is not approved for human consumption and is strictly intended for laboratory research purposes only.

What is 3-CL-PCP?

3-CL-PCP is a halogenated analog of PCP. It contains a chlorine substituent on the phenyl ring, which may influence its binding affinity and duration of action. It belongs to a class of compounds studied for their anesthetic, dissociative, and neurochemical properties in controlled settings.

  • IUPAC Name: 1-(1-(3-chlorophenyl)cyclohexyl)piperidine

  • Molecular Formula: C17H26ClN

  • Chemical Class: Arylcyclohexylamine, dissociative anesthetic

  • Typical Form: White crystalline powder

While little formal data exists, its core structure suggests NMDA receptor antagonism as its likely mechanism of action — similar to PCP and ketamine.

Reported Effects (Anecdotal)

Anecdotal reports from research forums and independent chemists suggest that 3-CL-PCP may produce dissociative effects similar to PCP analogs, though individual responses and potencies can vary widely.

Potentially reported effects include:

  • Detachment from physical environment (dissociation)

  • Altered perception of time, body, and space

  • Reduced pain perception

  • Impaired motor coordination

  • Cognitive disconnection

These effects are purely observational and have not been scientifically verified. No medical, clinical, or therapeutic uses are approved.

Safety and Handling

Due to the limited toxicological and pharmacokinetic data, 3-CL-PCP must be handled with extreme caution. Exposure may result in unintended neurochemical interactions or laboratory incidents.

Potential safety concerns include:

  • Overstimulation of the CNS or confusion

  • Coordination impairment

  • Anxiety or disorientation

  • Respiratory and cardiovascular strain

  • Unknown long-term effects

All laboratory work should be performed by qualified professionals using PPE, appropriate containment, and verified safety protocols. It is not suitable for field or unsupervised handling.

Legal Status of 3-CL-PCP

Legal classification of 3-CL-PCP varies across jurisdictions and is evolving as authorities expand regulation of designer dissociatives.

  • United States: Not federally scheduled, but may be subject to the Federal Analog Act

  • United Kingdom: May fall under Class B substances via the Misuse of Drugs Act, depending on interpretation

  • Germany: Controlled under the NpSG (New Psychoactive Substances Act)

  • European Union: Status varies by country; typically monitored as an NPS

  • Australia & Canada: May be regulated under analog control frameworks

Researchers should verify all applicable legal guidelines before procurement or analysis.

For Research Use Only

3-CL-PCP is provided solely for academic, forensic, and scientific research. It is not intended for human or veterinary use. All activities involving this compound must comply with local, national, and international regulations.

Improper handling, misuse, or distribution may result in serious legal and health consequences.

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