3-Me-PCE

3-Me-PCE: Research Chemical Profile, Structure, and Legality

3-Me-PCE (3-Methyleticyclidine) is a dissociative compound belonging to the arylcyclohexylamine family, structurally related to PCE and 3-MeO-PCE. It has drawn scientific interest due to its interaction with the NMDA receptor system, which is commonly associated with dissociative anesthetic effects in laboratory studies.

3-Me-PCE is offered strictly for analytical, chemical, and pharmacological research and is not approved for human or veterinary use.

Chemical Information and Properties

As a methyl-substituted analog of eticyclidine (PCE), 3-Me-PCE has a unique structural arrangement that may affect its potency and receptor binding profile. The addition of a methyl group at the 3-position on the phenyl ring is thought to influence both duration and efficacy.

  • IUPAC Name: N-Ethyl-1-(3-methylphenyl)cyclohexan-1-amine

  • Molecular Formula: C15H23N

  • Chemical Class: Arylcyclohexylamine, dissociative anesthetic

  • Form: Typically a crystalline powder or solid

  • Use: For research and forensic study only

Due to its relatively recent emergence, formal toxicological data on 3-Me-PCE remains limited. It is primarily examined in in vitro assays and receptor affinity models.

Reported Effects (Anecdotal)

Although not backed by clinical trials, anecdotal data from chemical research communities suggest that 3-Me-PCE may produce dissociative effects somewhat similar to other arylcyclohexylamines like 3-MeO-PCE or ketamine, with its own distinct activity profile.

Reported effects (in controlled settings) may include:

  • Dissociation and sensory detachment

  • Altered perception of time and environment

  • Numbing or anesthetic-like sensations

  • Disruption of motor coordination

  • Mild stimulant-like properties in low concentrations

These effects are speculative and should not be interpreted as therapeutic or safe. 3-Me-PCE is not intended for any form of ingestion or in vivo study in humans.

Safety Information and Handling

Due to the limited understanding of its toxicity and pharmacokinetics, 3-Me-PCE must be handled with full laboratory precautions. Proper safety equipment and protocols are mandatory during research.

Key safety considerations:

  • Potential neurotoxicity with unknown thresholds

  • Risk of psychological disturbances at high exposure

  • Inhalation or skin contact may pose unknown risks

  • Should not be used in any clinical or unsupervised setting

All handling should occur in a certified laboratory with personal protective equipment (PPE) and appropriate containment.

Legal Status of 3-Me-PCE

The legal classification of 3-Me-PCE differs by jurisdiction and may fall under analog or psychoactive substance laws depending on local interpretation.

  • United States: Not scheduled federally; may be controlled under the Federal Analog Act

  • United Kingdom: Potentially covered under the Psychoactive Substances Act (PSA)

  • Germany: Likely restricted under the NpSG (New Psychoactive Substances Act)

  • Canada & Australia: May be considered a controlled substance under general analog regulations

  • EU: Status varies across member states; often under review as an NPS (new psychoactive substance)

Researchers must verify current regulations before purchasing or handling this compound.

For Research Use Only

3-Me-PCE is not approved for human or animal consumption and is intended for laboratory research, forensic analysis, and academic study only. Use must be in accordance with all applicable laws and safety standards.

Unauthorized use, distribution, or possession may result in serious legal consequences.

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