3-Me-PCP

3-Me-PCP: Research Chemical Profile, Effects, and Legal Overview

3-Me-PCP (3-Methylphencyclidine) is a dissociative research chemical belonging to the arylcyclohexylamine family. It is structurally related to PCP (phencyclidine) and shares similar activity as an NMDA receptor antagonist, making it of interest in neurochemical and pharmacological research.

This compound is not approved for human or veterinary use and is supplied strictly for analytical and scientific research in qualified laboratory settings.

Chemical Profile

3-Me-PCP is a methylated analog of PCP, with a methyl group positioned at the 3-location of the phenyl ring. This substitution may influence its receptor binding characteristics, potency, and duration of action when studied in vitro.

  • IUPAC Name: 1-[1-(3-methylphenyl)cyclohexyl]piperidine

  • Molecular Formula: C18H27N

  • Chemical Class: Arylcyclohexylamine, dissociative anesthetic

  • Appearance: White or off-white crystalline powder

  • Form: Typically provided as hydrochloride or freebase for lab use

Due to its similarity to other dissociatives like 3-MeO-PCP, it is often studied for structure-activity relationships (SAR) in NMDA receptor research.

Reported Effects (Anecdotal)

While 3-Me-PCP has not been formally evaluated in clinical settings, anecdotal reports from research forums suggest that it produces effects comparable to other PCP analogs, with its own unique profile.

Possible observed effects (from research reports) include:

  • Dissociation from environment or body

  • Altered sensory perception and motor control

  • Time distortion or introspective states

  • Cognitive detachment or confusion

  • Mild euphoria or emotional flattening

These effects are speculative and based on user-reported data. The compound has no approved medical application and should be handled exclusively by trained professionals.

Laboratory Handling and Safety

Because 3-Me-PCP’s toxicology and pharmacokinetics remain under-researched, all lab handling must follow strict safety protocols.

Key safety considerations:

  • May cause neurochemical disruption at certain concentrations

  • Unknown risk profile for long-term exposure

  • Potential for psychological effects during accidental exposure

  • Always use PPE, ventilation systems, and proper storage

Personnel should be qualified in working with potentially psychoactive materials under controlled conditions.

Legal Classification

The legal status of 3-Me-PCP is fluid and depends on each country’s approach to novel psychoactive substances (NPS) and analog laws.

  • United States: Not scheduled federally, but may be controlled under the Federal Analog Act due to similarity to PCP

  • United Kingdom: Potentially covered under the Misuse of Drugs Act (Class B) or Psychoactive Substances Act

  • Germany: Likely controlled under the NpSG (New Psychoactive Substances Act)

  • Canada & Australia: May fall under broad-spectrum dissociative controls

  • European Union: Regulation varies between member states and is often subject to review

Researchers should always consult their local regulations before acquiring or working with this substance.

For Research Use Only

3-Me-PCP is not for human consumption and is intended exclusively for forensic, analytical, and academic research. All use must comply with applicable laws and safety standards. Any misuse may result in legal consequences or health risks.

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