3F-PCP (3-FLUORO-PCP)

3F-PCP (3-Fluoro-PCP): Research Chemical Overview and Legal Status

3F-PCP (3-Fluorophencyclidine), also known as 3-Fluoro-PCP, is a synthetic compound belonging to the arylcyclohexylamine family. It is structurally related to phencyclidine (PCP) and 3-MeO-PCP, with a fluorine atom replacing a hydrogen atom at the 3-position on the phenyl ring. This seemingly minor substitution can lead to measurable differences in receptor affinity, pharmacokinetics, and in vitro effects, making it a relevant subject of research in neurochemistry and pharmacology.

3F-PCP is not approved for human or veterinary use. It is distributed solely for forensic, analytical, or scientific research purposes.

---

Chemical Information

3F-PCP is classified as a dissociative arylcyclohexylamine. It is often studied for its potential interaction with the NMDA receptor, which is involved in the modulation of memory, learning, and consciousness. The presence of the fluorine atom may influence both lipophilicity and receptor binding behavior, making it valuable in structure-activity relationship (SAR) studies.

• IUPAC Name: 1-[1-(3-fluorophenyl)cyclohexyl]piperidine

• Molecular Formula: C17H24FN

• Chemical Class: Arylcyclohexylamine, dissociative anesthetic analog

• Form: Typically available as a white crystalline powder or solid

• Applications: Receptor mapping, pharmacological screening, comparative analysis

---

Reported Effects (Anecdotal)

Though there is no clinical research on 3F-PCP, anecdotal data from research forums suggests that it may share many behavioral and psychotropic characteristics with other PCP analogs.

Reported effects (from informal user reports) include:

• Dissociation from physical or mental perception

• Altered sensory input and time perception

• Motor disruption or imbalance

• Cognitive distortion or introspection

• Dose-dependent stimulation or sedation

These effects are not validated and are presented only to inform scientific context.

---

Laboratory Handling and Safety

Because 3F-PCP is a potent dissociative compound, proper handling procedures are critical. It should only be used by trained personnel in facilities equipped for chemical research.

Standard precautions include:

• Use of gloves, lab coat, and protective eyewear

• Handling within a chemical fume hood

• Accurate measurement using microgram-scale instruments

• Storage in labeled, sealed containers away from heat and moisture

• Disposal in accordance with institutional hazardous waste protocols

No clinical or long-term toxicological studies are available, so all work with 3F-PCP should be approached conservatively.

---

Legal Status

The legal classification of 3F-PCP varies widely by region and is often governed by analogue laws, psychoactive substance acts, or inclusion under broader arylcyclohexylamine restrictions.

• United States: Not scheduled at the federal level; may be regulated under the Federal Analog Act

• United Kingdom: May fall under the Misuse of Drugs Act or Psychoactive Substances Act (PSA)

• Germany: Potentially restricted under the NpSG (New Psychoactive Substances Act)

• Canada & Australia: May be controlled as an analog of PCP

• European Union: Regulation varies by country and may be under review

Researchers are responsible for verifying local laws before procuring or using 3F-PCP in any setting.

---

For Research Use Only

3F-PCP is not intended for human consumption or medical use. It is supplied strictly for laboratory, forensic, or analytical research by qualified professionals. All usage must comply with applicable laws and safety protocols.