5-MMPA (Mephedrene)

5-MMPA (Mephedrene): Research Chemical Overview, Effects, and Legal Status

5-MMPA, also known as Mephedrene, is a novel synthetic stimulant that belongs to the substituted cathinone family, a group of compounds known for their psychoactive and stimulant-like effects in laboratory research. Though relatively new to the research chemical scene, 5-MMPA has attracted interest for its structural similarity to other well-known cathinones like mephedrone (4-MMC) and methcathinone.

What is 5-MMPA?

Chemically, 5-MMPA is a substituted cathinone with a methoxy substitution on the phenyl ring, which may affect its binding properties and pharmacological profile. It is typically studied for its stimulant potential, molecular behavior, and forensic relevance.

• IUPAC Name: 2-(methylamino)-1-(5-methoxyphenyl)pentan-1-one

• Molecular Formula: C13H19NO2

• Common Names: Mephedrene, 5-MMPA

• Chemical Class: Cathinone, stimulant analog

Reported Effects (In Research Settings)

Although formal toxicological and pharmacological studies are limited, early user reports and lab observations suggest that 5-MMPA may produce stimulant-like effects similar to other synthetic cathinones. These may include:

• Increased energy and stimulation

• Heightened alertness and focus

• Mild euphoria or mood enhancement

• Reduced appetite

• Possible empathogenic effects

As with all research chemicals, effects can vary widely depending on dosage, purity, and individual response. No human or animal use is approved.

Safety and Toxicology

Because 5-MMPA is a new and unregulated compound, very little is known about its short-term or long-term safety. Based on structural analogs, it may carry potential risks such as:

• Cardiovascular strain (e.g., tachycardia, hypertension)

• Central nervous system overstimulation

• Possible neurotoxicity

• Psychological effects such as anxiety or irritability

• Unknown interaction profile

All handling should be done by qualified professionals in controlled laboratory settings, using appropriate safety protocols and personal protective equipment (PPE). It is not for human consumption.

Legal Status

As of now, 5-MMPA (Mephedrene) is not explicitly scheduled in many countries, but its legal status is rapidly evolving. It may be covered under analogue or blanket substance laws in various jurisdictions.

• United States: Not scheduled federally but may fall under the Federal Analog Act

• United Kingdom: Likely banned under the Psychoactive Substances Act

• Germany & EU: May be controlled under new psychoactive substance regulations

• Canada, Australia, China: Subject to regional analog legislation

Researchers must ensure compliance with all local and international regulations before handling or importing this substance.

Research Use Only Disclaimer

This compound is intended strictly for scientific, analytical, and forensic research. 5-MMPA (Mephedrene) is not approved for human or veterinary use. It should only be purchased and handled by qualified entities operating within the bounds of applicable laws.