DPT (N-dipropyltryptamine)

DPT (N,N-Dipropyltryptamine): Research Chemical Overview and Applications

DPT, or N,N-Dipropyltryptamine, is a synthetic tryptamine compound known for its structural similarity to naturally occurring indole alkylamines such as DMT (N,N-Dimethyltryptamine). As a member of the tryptamine class, DPT is studied extensively in neuropharmacology, serotonin receptor analysis, and analytical chemistry.

It is not intended for human consumption and is supplied solely for scientific research purposes, including in vitro studies and forensic analysis.

---

Chemical and Structural Profile

• Chemical Name: N,N-Dipropyltryptamine

• Molecular Formula: C16H26N2

• IUPAC Name: 3-[2-(Dipropylamino)ethyl]indole

• Chemical Class: Tryptamine / Indolealkylamine

• Physical Appearance: White to off-white powder or crystalline solid

• Common Use: Laboratory research on serotonin pathways and SAR (structure–activity relationships)

DPT is differentiated from DMT by the replacement of methyl groups with propyl chains, which significantly alters its pharmacokinetic and receptor-binding properties.

---

Research and Analytical Applications

DPT is a subject of interest in multiple scientific disciplines. Its use cases include:

• 5-HT2A receptor interaction studies

• Structure–activity relationship comparison with DMT and other tryptamines

• Toxicology screenings in forensic research

• Analytical method development (e.g., LC-MS, GC-MS, FTIR)

• Pharmacological modeling in computational simulations

Its longer alkyl chains make it particularly interesting for researchers studying binding affinity modulation within the serotonin system.

---

Laboratory Characteristics

While no approved clinical studies are available, laboratory investigations and theoretical modeling suggest:

• DPT interacts with serotonin receptors, particularly 5-HT2A

• It is lipophilic, allowing for potential blood–brain barrier permeability in models

• Its propyl substitutions increase metabolic resistance compared to DMT

• It may influence downstream serotonin-related signaling pathways in vitro

All usage must comply with strict research guidelines and safety standards.

---

Legal Status

The legal classification of DPT varies by country and is often influenced by analog legislation:

• United States: Not scheduled at the federal level, but may be considered illegal under the Federal Analog Act

• United Kingdom: Controlled under the Psychoactive Substances Act

• Germany: Potentially controlled under NpSG (New Psychoactive Substances Act)

• Australia and Canada: Varies by province and federal law

• EU Member States: Classification may depend on structural analog laws

Researchers are responsible for verifying the legality of DPT in their jurisdiction before handling or acquiring the compound.

---

Safety and Handling Guidelines

DPT is for research use only. It is not approved for therapeutic, dietary, or recreational use. All handling must be performed by qualified laboratory personnel.

Safety best practices include:

• Use of gloves, safety goggles, and lab coats

• Working within a fume hood or ventilated space

• Secure and labeled storage in a cool, dry environment

• Accurate weighing using laboratory-grade microbalances

• Compliance with chemical waste disposal regulations

---

For Research Use Only

DPT (N,N-Dipropyltryptamine) is strictly intended for laboratory research, analytical reference, or forensic purposes. It is not intended for human or veterinary use under any circumstances.