EPT (Ethylpropyltryptamine)

EPT (Ethylpropyltryptamine): Research Chemical Profile and Scientific Use

EPT, or Ethylpropyltryptamine, is a synthetic tryptamine-based compound studied for its potential relevance in serotonin receptor research, forensic toxicology, and structure–activity relationship (SAR) analysis. It belongs to the same chemical family as DMT and DET, differing primarily by its N-substitution pattern — one ethyl and one propyl group replacing the typical dimethyl substitutions found in DMT.

EPT is not intended for human consumption and is available exclusively for research and analytical purposes in controlled laboratory environments.

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Chemical and Structural Overview

• Full Name: N-Ethyl-N-propyltryptamine

• Chemical Class: Substituted tryptamine / Indolealkylamine

• Molecular Formula: C15H24N2

• IUPAC Name: N-ethyl-N-propyl-2-(1H-indol-3-yl)ethanamine

• Common Forms: Fumarate or hydrochloride salt; crystalline or powdered

• Usage Context: Laboratory-based research in neuroscience and analytical chemistry

As a structural analog of DMT and other monoalkyl tryptamines, EPT provides researchers with a compound to assess the effects of longer alkyl chains on serotonin receptor binding, metabolism, and pharmacokinetics.

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Research Applications

EPT is used in a range of scientific studies and laboratory settings. Its primary research applications include:

• Binding affinity analysis at 5-HT2A and related serotonin receptors

• Comparative pharmacology within the tryptamine class

• Analytical standard development in toxicology or forensic detection

• SAR modeling in synthetic neurochemistry

• Metabolite profiling using GC-MS and LC-MS techniques

Its ethyl and propyl substitutions make EPT a unique compound for studying the effect of asymmetrical N-substitutions in tryptamines.

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Observed Laboratory Characteristics

In silico models and limited in vitro data suggest the following characteristics:

• Moderate to high serotonin receptor affinity, particularly 5-HT2A

• Lipophilic nature, supporting ease of membrane penetration

• Likely slower metabolic breakdown compared to dimethyl tryptamines

• Similar indole core structure to endogenous serotonin analogs

All experimentation must be carried out under controlled lab conditions with strict adherence to chemical handling procedures.

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Legal Status

As of now, EPT is not scheduled under most international drug control treaties, though it may be regulated under analog or psychoactive substance laws depending on the country.

• United States: Not federally scheduled, but may be considered an analog under the Federal Analog Act

• United Kingdom: May fall under the Psychoactive Substances Act 2016

• Germany: Likely covered by the NpSG (New Psychoactive Substances Act)

• Canada & Australia: Subject to analog-based regulatory interpretation

• EU: Legal status varies by country

It is the researcher’s responsibility to ensure compliance with local and national laws prior to acquiring or using this compound.

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Handling and Safety Precautions

EPT is for research use only and is not approved for human or veterinary consumption. Safe handling procedures must always be followed in a qualified laboratory setting.

Recommended safety measures include:

• Use of gloves, lab coats, and eye protection

• Storage in a cool, dry, and secure environment

• Handling within fume hoods or ventilated enclosures

• Precision weighing using calibrated microgram balances

• Proper documentation and waste disposal

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For Research Use Only

EPT (Ethylpropyltryptamine) is intended strictly for scientific, analytical, and forensic research. It must not be used for recreational, therapeutic, or dietary purposes.