Methoxpropamine (MXPr)
Methoxpropamine (MXPr): Research Chemical Overview and Legal Status
Methoxpropamine, commonly abbreviated as MXPr, is a dissociative research chemical belonging to the arylcyclohexylamine family. It is structurally related to ketamine and methoxetamine (MXE), with unique properties that make it an important subject in neurochemical and receptor-level studies.
MXPr is used in in vitro NMDA receptor analysis, structure-activity relationship (SAR) research, and analytical method development. It is offered strictly for scientific research and is not intended for human or veterinary use.
Chemical Characteristics
MXPr distinguishes itself with a propylamino side chain, unlike the ethyl group found in methoxetamine (MXE). This alteration may impact its binding affinity, onset, and duration, which researchers find valuable for comparative pharmacological studies.
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IUPAC Name: 2-(1-methoxyphenyl)-2-(propylamino)cyclohexanone
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Molecular Formula: C16H25NO2
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Chemical Class: Arylcyclohexylamine, dissociative anesthetic analog
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Appearance: White or off-white crystalline powder
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Common Applications: NMDA antagonist modeling, forensic toxicology, analytical reference
Its close relationship to ketamine makes MXPr relevant for investigating novel dissociatives and their interaction with glutamate pathways.
Anecdotal Reports (Unverified)
While MXPr has not undergone clinical or toxicological evaluation, anecdotal data from independent research forums suggest dissociative effects broadly similar to ketamine or MXE, with a few notable distinctions.
Reported (non-clinical) characteristics include:
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Mental dissociation and visual distortion
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Altered perception of time and body
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Smooth onset and extended duration
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Subtle stimulation or emotional detachment
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Lower intensity compared to MXE (varies by dose)
These observations are unverified and shared for informational purposes only. They should not replace formal laboratory data.
Laboratory Handling and Safety Guidelines
Due to limited human safety data, MXPr must be handled with strict laboratory safety protocols. Only professionals in licensed research environments should work with this compound.
Recommended handling procedures:
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Use of gloves, goggles, and protective clothing
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Work conducted in a chemical fume hood
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Accurate microgram-level measurement
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Secure, labeled storage in a temperature-controlled setting
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Disposal in accordance with hazardous waste guidelines
Safe handling helps mitigate unknown risks associated with novel research chemicals.
Legal Status of Methoxpropamine (MXPr)
MXPr’s legal classification varies depending on country-specific regulations. While it may not be explicitly scheduled, it could be controlled under analog or blanket psychoactive substance laws.
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United States: Not federally scheduled; may fall under the Federal Analog Act
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United Kingdom: May be restricted under the Psychoactive Substances Act (PSA)
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Germany: Likely controlled under the NpSG (New Psychoactive Substances Act)
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Canada & Australia: Subject to analog provisions or local chemical control laws
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European Union: Legal status varies between member states
Researchers must confirm the status of MXPr in their jurisdiction before acquisition or study.
For Research Use Only
Methoxpropamine (MXPr) is not approved for human or veterinary use. It is provided solely for scientific, forensic, or analytical purposes by qualified individuals operating in compliance with applicable laws.
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