MXP (Methoxphenidine)
Methoxphenidine (MXP): Research Chemical Profile and Legal Overview
Methoxphenidine, commonly abbreviated as MXP, is a dissociative compound in the diarylcyclohexylamine class. It is closely related to other NMDA receptor antagonists like diphenidine, ketamine, and MXE. MXP is primarily used in receptor-binding assays, pharmacological modeling, and structure-activity relationship (SAR) research.
This compound is offered exclusively for laboratory research purposes and is not intended for human or veterinary use.
Chemical Structure and Classification
MXP features a methoxy substitution on the phenyl ring, which differentiates it from diphenidine and contributes to its unique receptor affinity and pharmacological properties. It has been the subject of interest in studies examining its dissociative potential and NMDA antagonistic activity.
-
IUPAC Name: 1-[1-(2-methoxyphenyl)-2-phenylethyl]piperidine
-
Molecular Formula: C20H25NO
-
Chemical Class: Diarylcyclohexylamine (Dissociative)
-
Appearance: Typically a white or off-white crystalline powder
-
Common Applications: NMDA receptor research, SAR studies, forensic toxicology
MXP has a more rigid and less flexible structure compared to ketamine analogs, which may impact its duration and binding efficiency in vitro.
Anecdotal Effects (Unverified Research Reports)
MXP has not been approved for clinical use, and its effects are not documented in peer-reviewed pharmacological literature. However, anecdotal data suggest that it may produce dissociative effects similar to other arylcyclohexylamines.
Reported (non-verified) properties include:
-
Perceptual distortion and dissociative states
-
Altered sensory processing
-
Long-lasting duration compared to ketamine
-
Limited euphoria, with a focus on cognitive detachment
-
Reduced motor coordination (based on anecdotal descriptions)
These observations are presented for informational context only and should not be treated as clinical findings.
Laboratory Safety and Handling
Due to its limited toxicological profile, MXP should only be handled by trained professionals in secure laboratory environments. Proper procedures must be followed to ensure safety and research integrity.
Recommended laboratory protocols:
-
Use of protective gloves, eyewear, and lab coats
-
Work in a well-ventilated or filtered lab space
-
Microgram-accurate measurement tools
-
Secure, labeled chemical storage
-
Disposal in accordance with chemical safety regulations
MXP should not be consumed or tested outside of approved laboratory settings.
Legal Status of Methoxphenidine (MXP)
MXP’s legality varies by country and may be affected by both controlled substance scheduling and analogue legislation. It is the researcher’s responsibility to verify compliance with local laws prior to acquisition.
-
United States: Not scheduled federally; may fall under Federal Analog Act
-
United Kingdom: Controlled under the Misuse of Drugs Act (Class B)
-
Germany: Likely restricted under the NpSG
-
Canada: May fall under analogue controls
-
Australia & EU: Subject to national analogue or psychoactive substance regulations
Its presence on international watchlists has increased over time due to its structural similarity to MXE and diphenidine.
For Research Use Only
Methoxphenidine (MXP) is not approved for human or veterinary consumption. It is intended solely for scientific, forensic, and analytical research conducted by qualified professionals in legally authorized laboratories.
Showing the single result