NB-5-MeO-MiPT

NB-5-MeO-MiPT: Research Chemical Profile and Analytical Overview

NB-5-MeO-MiPT is a synthetic compound belonging to the tryptamine chemical class and is structurally related to the well-known molecule 5-MeO-MiPT. The “NB” prefix suggests a N-benzyl substitution on the tryptamine backbone, which may significantly influence the compound’s binding profile and pharmacological characteristics.

This compound is utilized in neuroscientific, analytical, and pharmacological research to explore its interaction with serotonin receptors, particularly 5-HT2A, and its structural variations from naturally occurring tryptamines.

Chemical Profile

  • Full Name: N-Benzyl-5-methoxy-N-methyl-N-isopropyltryptamine

  • Chemical Class: Substituted tryptamine / N-Benzyl derivative

  • Molecular Formula: Likely derived from 5-MeO-MiPT with a benzyl group addition

  • Appearance: Generally supplied as a powder or crystalline solid

  • Common Use: Scientific reference material and neurochemical research

NB-5-MeO-MiPT is part of a newer wave of designer tryptamines developed to examine structure–activity relationships (SAR) and assess how various substitutions alter pharmacodynamic effects.

Research Applications

NB-5-MeO-MiPT is a candidate for various research domains including:

  • Serotonergic receptor binding assays

  • Comparative structure-function analysis with 5-MeO-MiPT and related compounds

  • Analytical profiling (GC-MS, LC-MS, NMR)

  • Toxicological research in controlled laboratory settings

  • Development of detection protocols in forensic science

Due to its unique molecular substitution, researchers are particularly interested in its receptor affinity modulation compared to its base compound.

Observed Characteristics in Research Settings

Although no formal pharmacological data is available publicly, the addition of an N-benzyl group typically:

  • Increases lipophilicity, potentially affecting brain penetration

  • May modify binding strength to 5-HT2A/5-HT1A receptors

  • Alters metabolic pathways and enzymatic degradation rates

  • Offers a distinct pharmacological fingerprint for SAR studies

All testing is to be conducted in certified research facilities under appropriate controls.

Legal Status

NB-5-MeO-MiPT is a novel research chemical and may not be explicitly scheduled in many countries. However, its classification is often inferred from structural similarity to scheduled substances.

  • United States: Not scheduled federally, but could be restricted under the Federal Analog Act

  • United Kingdom: May fall under the Psychoactive Substances Act 2016

  • Germany: Potentially covered under NpSG

  • European Union and Canada: Status varies; legal responsibility rests with the researcher

  • Australia & New Zealand: Generally restricted under analog laws

Always verify with national regulatory bodies before acquisition or use.

Safety and Handling

NB-5-MeO-MiPT is not approved for human or veterinary consumption. It must be handled exclusively by trained professionals in licensed research environments.

Standard laboratory safety includes:

  • Proper use of PPE (gloves, goggles, lab coat)

  • Chemical-grade storage containers in cool, dry environments

  • Weighing with precision microgram balances

  • Documentation and traceability of all research procedures

  • Adherence to local chemical safety and disposal regulations

For Research Use Only

NB-5-MeO-MiPT is supplied strictly for scientific, forensic, or analytical purposes. It is not intended for human use, and any other application is strictly prohibited.

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